Autologous transplantation of CD133 + BM-derived stem cells as a therapeutic option for dilatative cardiomyopathy.

Autor:	Ghodsizad, A., Ruhparwar, A., Marktanner, R., Borowski, A., Mohammad Hasani, M. R., Poll, L., Vshivkov, I., Stoldt, V., Voelkel, T., Piechaczek, C., Burchardt, E. R., Stockschlaeder, M., Sucker, C., Gams, E., Klein, H. M.
Předmět:	CARDIOMYOPATHIES ECHOCARDIOGRAPHY MAGNETIC resonance CELL transplantation CARDIAC imaging SURGERY
Zdroj:	Cytotherapy (Taylor & Francis Ltd); Jun2006, Vol. 8 Issue 3, p308-310, 3p, 1 Diagram, 1 Graph
Abstrakt:	We report the case of a 58-year-old man with end-stage non-ischemic cardiomyopathy. Baseline transthoracic echocardiography (TTE) and cardiac magnetic resonance (cMRI) revealed a markedly depressed left ventricle systolic function. He underwent autologous CD133 + BM-derived cell transplantation through a minimally invasive approach. During surgery 19×10 6 BM-derived stem cells were injected by the transepimyocardial route. Six months after the operation TTE and cMRI showed a clear improvement in left ventricular contractility. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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