Clinical outcome of 36 male patients with primary urethral carcinoma: A single center experience.

Autor: Thyavihally, Yuvaraja B., Tongaonkar, Hemant B., Srivastava, Shyam K., Mahantshetty, Umesh, Kumar, Prabhash, Raibhattanavar, Srinivas G.
Předmět:
Zdroj: International Journal of Urology; Jun2006, Vol. 13 Issue 6, p716-720, 5p, 3 Charts, 1 Graph
Abstrakt: Aim: Retrospective analysis of male urethral carcinoma to assess the best therapeutic approach to the management of this tumor. Methods: A review of 36 cases of male urethral carcinoma diagnosed and treated at our center was performed. Clinical features, treatment modality and outcomes were analysed. Results: The overall median survival time was 55.16 months. The 5-year overall and disease-free survival rate for the cohort was 49% and 23%, respectively. The 5-year survival is 67% for low-stage versus 33% for high-stage tumors and is significantly different ( P = 0.001). The survival was 72% for tumors of the distal urethra versus 36% for tumors of the proximal, with a P-value of 0.02. Conclusion: The tumor location and clinicopathological stage were the most important predictors of the disease-free and overall survival. Multimodal approach is necessary for achieving local control especially for proximal and higher stage tumors. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index