Wide-range C-reactive protein efficacy in acute ischemic stroke patients.

Autor: Shenhar-Tsarfaty, S., Ben Assayag, E., Bova, I., Vered, Y., Berliner, S., Rogowski, O., Shapira, I., Bornstein, N. M.
Předmět:
Zdroj: Acta Neurologica Scandinavica; Jul2006, Vol. 114 Issue 1, p29-32, 4p, 2 Charts, 1 Graph
Abstrakt: Objective – To compare the recently introduced wide-range C-reactive protein (wr-CRP) with the widely used high-sensitivity Behring Dade method (hs-CRP) in acute stroke/transient ischemic attack (TIA) patients. Materials and methods – A total of 119 consecutive patients admitted to a tertiary medical center with acute ischemic stroke/TIA were included in the study. Venous blood was obtained for both assays during the first 24 h, 3–5 days, as well as 3–6 months thereafter. Results – A highly significant correlation ( r = 0.994, P < 0.0001) was found between the two methods even when analyzed at three different time points. In addition, a similar correlation was noted between these two assays and other commonly used biomarkers, including white blood cell count, Westergren's sedimentation rate and quantitative fibrinogen. Conclusion – Real-time, on-line and low-cost wr-CRP assay is a reasonable alternative to the Behring Dade hs-CRP method in acute stroke/TIA patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index