| Autor: |
Mahy, P., De Bast, M., Gillart, J., Labar, D., Grégoire, V. |
| Předmět: |
|
| Zdroj: |
European Journal of Nuclear Medicine & Molecular Imaging; May2006, Vol. 33 Issue 5, p553-556, 4p, 1 Color Photograph, 1 Chart, 2 Graphs |
| Abstrakt: |
In the framework of the preclinical validation of the hypoxic tracer [18F]EF3, a comparison was performed between uptake of [18F]EF3 and EF5 adducts detected by immunofluorescence in MCa-4, FSA, FSAII, Sa-NH and NFSA tumour-bearing mice. Mice were allowed to breath carbogen (5% CO2, 95% O2), 21% oxygen or 10% oxygen. A significant correlation ( r 2=0.57; p<0.01) was found between the [18F]EF3 tumour-to-muscle ratio and the fluorescence intensity of EF5. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
