A case of hepatosplenic γ– δ T-cell lymphoma with a transient response to Fludarabine and Alemtuzumab.

Autor: Mittal, S., Milner, B. J., Johnston, P. W., Culligan, D. J.
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Zdroj: European Journal of Haematology; Jun2006, Vol. 76 Issue 6, p531-534, 4p, 1 Graph
Abstrakt: Hepatosplenic γ– δ T-cell lymphoma is a rare, usually fatal lymphoma and available literature on management is sparse. Allografting is probably the only curative option. We describe a further case with a dramatic, though transient response to Fludarabine and Alemtuzumab combination, following a failure of conventional chemotherapy. Given the dreadful prognosis with conventional chemotherapy, it is a regimen worth pursuing as a disease reduction strategy prior to allograft where appropriate. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index