Study of Blood Selenium Level in Thyroid Pathologies by Instrumental Neutron Activation Analysis.

Autor: Benamer, S., Aberkane, L., Benamar, M.A.
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Zdroj: Instrumentation Science & Technology; Jul/Aug2006, Vol. 34 Issue 4, p417-423, 7p, 2 Charts, 1 Graph
Abstrakt: Selenium deficiency constitutes a risk factor for several pathologies (congestive cardiomyopathie, cancer, etc.). It was shown, recently, that selenium is implied in thyroid metabolism. It constitutes the catalytic site of the enzymes intervening in thyroid hormone synthesis. In the present work, we determined concentrations of selenium in total blood of 39 patients suffering from thyroid pathologies (hyperthyroidism [HEP], hypothyrodism [HOP], simple goiter [SG]), and 29 normal controls using instrumental neutron activation analysis (INAA). The blood selenium concentrations of patients suffering from hyperthyroidism was 142.56±20.25 µg/L of total blood, which is significantly lower than that of normal controls (206.72±17.98 µg/L. p ≤0.05). No significant differences were observed in the concentrations of Se in hypothyroidism (184.26±20.77 µg/L) and simple goiter groups (160.47±25.76 µg/L). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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