| Autor: |
Jun Yu, Li Lei, Yuxin Liang, Hinh, Linda, Hickey, Reed P., Yan Huang, Dinggang Liu, Yeh, Jennifer L., Rebar, Edward, Case, Casey, Spratt, Kaye, Sessa, William C., Giordano, Frank J. |
| Předmět: |
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| Zdroj: |
FASEB Journal; Mar2006, Vol. 20 Issue 3, p479-481, 3p, 2 Diagrams, 2 Graphs |
| Abstrakt: |
Presents findings of a study on the biological effects of an engineered vascular endothelial growth factor (VEGFa)-activating zinc finger protein (ZFP) in a model of hindlimb ischemia. Role of the engineered ZFP transcription factor in activating VEGFa gene expression; Result of adenovirus-mediated expression of the CFP in skeletal muscle; Mechanism that results into a different expression profile of downstream angiogenesis-associated genes. |
| Databáze: |
Complementary Index |
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