| Autor: |
Ames, P. R. J., Delgado Alves, J., Lopez, L. R., Gentile, F., Margarita, A., Pizzella, L., Batuca, J., Scenna, G., Brancaccio, V., Matsuura, E. |
| Předmět: |
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| Zdroj: |
Clinical & Developmental Immunology; Mar2006, Vol. 13 Issue 1, p1-9, 9p, 1 Chart, 13 Graphs |
| Abstrakt: |
To explore whether antibodies against ß 2 -glycoprotein I (ß 2 GPI) complexed to 7-ketocholesteryl-9-carboxynonanoate (oxLig-1) and to oxidised low-density lipoproteins (oxLDL) relate to paraoxonase activity (PONa) and/or intima media thickness (IMT) of carotid arteries in primary antiphospholipid syndrome (PAPS). As many as 29 thrombotic patients with PAPS, 10 subjects with idiopathic antiphospholipid antibodies (aPL) without thrombosis, 17 thrombotic patients with inherited thrombophilia and 23 healthy controls were investigated. The following were measured in all participants: ß 2 GPI–oxLDL complexes, IgG anti-ß 2 GPI–oxLig-1, IgG anti-ß 2 GPI–oxLDL antibodies (ELISA), PONa, (para-nitrophenol method), IMT of common carotid (CC) artery, carotid bifurcation (B), internal carotid (IC) by high resolution sonography. ß 2 GPI–oxLDL complex was highest in the control group ( p [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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