| Autor: |
Whitaker, Donald C., Stygall, Jan, Hope-Wynne, Chris, Walesby, Robin K., Harrison, Michael J. G., Newman, Stanton P. |
| Předmět: |
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| Zdroj: |
Perfusion; Mar2006, Vol. 21 Issue 2, p83-86, 4p, 3 Charts |
| Abstrakt: |
Introduction: Microemboli are the main implicated cause of neuropsychological (NP) impairment after cardiac surgery. This prospective clinical trial compared the effect of an auto-venting arterial line filter on intraoperative cerebral microemboli and NP outcome compared to an arterial line filter with a vent line, in patients undergoing elective coronary artery bypass graft (CABG) surgery.Methods: One hundred and ten patients received either an Avecor Affinity (n = 73) or Pall AV-6 (n=37) control filter. Cerebral microemboli during cardiopulmonary bypass were recorded by transcranial Doppler monitoring of the right middle cerebral artery. Evidence of cerebral impairment was obtained by comparing patients' performance in a NP test battery (nine tests) administered 6–8 weeks postoperatively with their preoperative scores.Results: During cardiopulmonary by-pass, the median number and range of microemboli were 67 (5–846) and 55 (2–773) for the Avecor and AV-6 groups, respectively (p=0.47). There was no difference in NP outcome.Conclusion: There is no difference in the filtering ability of vent-line and auto-vent filters as assessed by cerebral microemboli. This, together with the similar NP outcome, suggests that both types of filter are equally safe for clinical use. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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