Induction of differentiation of pre-NKT cells to mature V ...14 NKT cells by granulocyte/...

Autor: Sato, Hiroshi, Nakayama, Toshinori
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America; 06/22/99, Vol. 96 Issue 13, p7439, 6p, 4 Graphs
Abstrakt: Describes a precursor population of V alpha 14 natural killer T (NKT) cells (pre-NKT) and characterized the molecular requirements for differentiation. Phenotype characterization of T cell antigen receptor (TCR) beta NKT cells in the TCR V beta8.2 spleen cells; Differentiation of pre-NKT cells into the mature NKT cells in vitro; Induction of V alpha 14 gene rearrangement in pre-NKT cells.
Databáze: Complementary Index