| Autor: |
Coolen, Marcel W., Van Loo, Karen M. J., Van Bakel, Nick N. H. M., Ellenbroek, Bart A., Cools, Alexander R., Martens, Gerard J. M. |
| Předmět: |
|
| Zdroj: |
FASEB Journal; Jan2006, Vol. 20 Issue 1, p175-177, 3p, 1 Diagram, 1 Graph |
| Abstrakt: |
The article discusses that reduced Aph-1b expression causes tissue- and substrate-specific changes in γ-secretase activity in rats with a complex phenotype. It was discussed that reduced Aph-1b expression levels are not compensated by its paralog Aph-1a. Tissue- and substrate-specific alterations in γ-secretase cleavage activity in rats with reduced Aph-1b levels was presented. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Plný text