Treatment targeted at vascular endothelial growth factor: a promising approach to managing metastatic kidney cancer.

Autor: Schrader, Andres J., Varga, Zoltan, Pfoertner, Susanne, Goelden, Ulrike, Buer, Jan, Hofmann, Rainer
Předmět:
Zdroj: BJU International; Mar2006, Vol. 97 Issue 3, p461-465, 5p, 1 Diagram
Abstrakt: The article reports on the relevance of vascular endothelial growth factor (VEGF) as a recombinant cytokine to generate and preserve tissue vasculature. The VEGF works by interacting with transmembrane tyrosine kinase receptors found on the cell surface, thus, enabling its proangiogenic protein effects.
Databáze: Complementary Index