Plasma 1,25-Dihydroxy- and 25-Hydroxyvitamin D and Subsequent Risk of Prostate Cancer.

Autor: Elizabeth A. Platz, Michael F. Leitzmann, Bruce W. Hollis, Walter C. Willett, Edward Giovannucci
Zdroj: Cancer Causes & Control; Apr2004, Vol. 15 Issue 3, p255-265, 11p
Abstrakt: Abstract Objective: The hormone 1,25-dihydroxyvitamin D (1,25(OH)2D) promotes prostate epithelial cell differentiation in vitro and thus, several groups have hypothesized that men who systemically have lower levels of 1,25(OH)2D may be at increased risk for prostate cancer. To address this hypothesis, we evaluated the association of circulating concentrations of 1,25(OH)2D and its precursor 25-hydroxyvitamin D (25(OH)D) with subsequent risk of prostate cancer. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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