Reactions of β-aroylacrylic acids with N-nucleophiles.

Autor: R. Khachikyan, N. Karamyan, H. Panosyan, M. Injikyan
Zdroj: Russian Chemical Bulletin; Aug2005, Vol. 54 Issue 8, p1982-1986, 5p
Abstrakt: Reactions of NH2OH·HCl with β-aroylacrylic acids proceed ambiguously: a nucleophile attacks either the carbonyl group or the C=C bond. In the latter case, the resulting α-hydroxyl-amino derivative converts into enamine, probably via dehydration followed by isomerization. Addition of 1,2,4-triazole to the C=C bond of β-(p-toluyl)acrylic acid followed by refluxing of their adduct with 60% NH2NH2·H2O gave a dihydropyridazinone derivative. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index