Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest.

Autor: Ishii, Mamoru, Jun Han, Hai-Yun Yen, Sucov, Henry M., Yang Chai, Maxson Jr, Robert E.
Předmět:
Zdroj: Development (09501991); Nov2005, Vol. 132 Issue 22, pN.PAG, 0p
Abstrakt: The article discusses the study "Combined Deficiencies of Msx1 and Msx2 Cause Impaired Patterning and Survival of the Cranial Neural Crest," by Mamoru Ishii, Henry M. Sucov et al. The study focused on the function of Msx1 and Msx2, homeobox genes implicated in several disorders affecting craniofacial development in humans. The change in the expression of the hindbrain markers Krox20 and Epha4 in Msx1/2 mutants suggests that defects in neural crest populations may result from defects in rhombomere identity.
Databáze: Complementary Index