| Autor: |
Juturu, V., Ruelle, A., Hudson, M. S., Komorowski, J. R. |
| Předmět: |
|
| Zdroj: |
Trace Elements & Electrolytes; 2006 1st Quarter, Vol. 23 Issue 1, p66-72, 7p |
| Abstrakt: |
Background: Glucose control remains the cornerstone of therapeutic strategies in patients with type 2 diabetes mellitus (DM). Clinical trial data suggest that chromium picolinate (CrPic) improves insulin sensitivity, glycemic control, and improved symptomatology in diabetes while biotin favorably affects abnormalities in glucose regulation. Methods: A I 2-week, open-labeled, nutrition and education program was conducted to determine the effects of a CrPic and biotin combination on glycemic control. Subjects (n = 30) with type 2 DM who had a base- line HbAlc ≥ 7% and were receiving oral antidiabetic medications for at least 6 months prior to the study were eligible for enrollment. The program included supplementation with (CrPic, 300 μg of Cr, and biotin 150 μg) twice daily, promotion of blood glucose monitor use, and provision of educational information on diabetes management. Pre- and post study levels of HbAlc were measured for each subject. Results: After 12 weeks, a significant drop was noted in subjects with baseline HbAlc from 8.5% to 7.4% with a mean change of 1.1% (p <0.01). No adverse events were reported. The subjects with medications responded significantly to the combination of CrPic and biotin. Conclusions: When used in conjunction with an educational feedback program and antidiabetic medications, the combination of CrPic and biotin (Diachrome®) is safe and effective in diabetes. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
