| Autor: |
Silva Jr., Michael B., Bohannon, W. Todd |
| Předmět: |
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| Zdroj: |
Perspectives in Vascular Surgery & Endovascular Therapy; Apr2004, Vol. 16 Issue 2, p153-154, 2p |
| Abstrakt: |
The use of abciximab in conjunction with infrainguinal angioplasty in 16 patients over an 18-month period in 1999 was investigated. Abciximab was given to patients thought to be at high risk for a thrombotic or embolic complication. Ten patients had high-grade stenoses or occlusions in the popliteal artery and superficial femoral artery; six patients had stenoses or occlusions below the popliteal artery. After arterial access was achieved, all patients received a bolus of heparin. A weight-based nomogram, consisting of an initial bolus followed by an overnight infusion, was used to administer the abciximab. A less than 30% residual stenosis after angioplasty was considered a technical success. Patients were monitored for complications following the procedure and platelet counts were monitored for 24 hours. Technical success occurred in 94% (15/16) of the patients. No significant effect on platelet count was noted. Two minor complications occurred. The major complication was a groin hematoma in a patient who was also undergoing chronic antiplatelet therapy with aspirin and clopidogrel. Abciximab has promise as an adjunct during complex infrainguinal arterial interventions but further study is needed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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