| Autor: |
Hyun Suk Whang, Kirsch, Wolff, Zhu, Yong H., Yang, Cheng Z., Hudson, Samuel M. |
| Předmět: |
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| Zdroj: |
Journal of Macromolecular Science: Polymer Reviews; Oct-Dec2005, Vol. 45 Issue 4, p309-323, 15p, 4 Diagrams, 1 Chart, 2 Graphs |
| Abstrakt: |
A recent review detailing the role of new hemostatic agents for battlefield hemorrhage control describes the interest in and necessary specifications for such materials. As a consequence, the Defense Department authorized the development and use of three deployable and FDA approved hemostatic agents: Zeolite “Quikclot” and chitosanic “Hemcon” and the American Red Cross Fibrin Dressing. Although chitosan has a number of advantages over the other hemostatic agents, it is the least understood of the three agents noted above. The use of chitosan and chitin in different physical forms as a hemostatic agent is described. The chemical properties of chitosan related to hemostatis possibly include: molecular weight, extent of ionization, counter ion, degree of deacetylation, and degree of crystallinity. Also, its ability to bind with tissues are a function of these parameters. Chitosan can be used in medical and surgical procedures by its direct application to a bleeding surface using the various physical forms such as powder, solution, coating, film, hydrogel, and filament composite. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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