| Autor: |
Vita, J. A. |
| Předmět: |
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| Zdroj: |
Heart; Oct2005, Vol. 91 Issue 10, p1278-1279, 2p |
| Abstrakt: |
The article presents information about abnormalities of endothelial function which are associated with worse clinical outcome in individuals at risk for atherosclerosis and in patients with established disease. The available evidence suggests that these alterations in endothelial phenotype contribute to the formation, progression, and rupture of atherosclerotic lesions. It is clear that endothelium regulates many aspects of vascular homeostasis. The clinical relevance of endothelial dysfunction for cardiovascular disease events is strongly supported by studies in the human coronary circulation. Despite the highly localized nature of plaque rupture in acute coronary syndromes, patients at risk for such events also display endothelial dysfunction in peripheral arteries. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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