Interferon-gamma decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting...

Autor: Youakim, Adel, Ahdieh, Minoo
Předmět:
Zdroj: American Journal of Physiology: Gastrointestinal & Liver Physiology; May99, Vol. 39 Issue 5, pG1279, 10p, 1 Color Photograph, 6 Graphs
Abstrakt: Investigates the effects of interferon (IFN)-gamma on tight junctions in T84 human intestinal epithelial cells. How IFN-gamma treatment reduces the levels of zonula occludens (ZO)-1 in T84 cells; How IFN-gamma treatment decreases ZO-1 protein synthesis and stability; How IFN-gamma treatment decreases the transcription of ZO-1.
Databáze: Complementary Index