Improved Synthesis of 1,3-Propanediol Derivatives Having a Diethoxyphosphoryldifluoroethyl Functional Group at the 2-Position: Application to Chemoenzymatic Synthesis of Novel Acyclic Nucleotide Analogues of Adenosine Bisphosphates .

Autor:	Tetsuo Murano, Hirokuni Kobayakawa, Yoko Yuasa, Tsutomu Yokomatsu, Shiroshi Shibuya
Předmět:	ADENOSINES PROPANE ADENINE PURINES
Zdroj:	Synthesis; Feb2005, Vol. 2005 Issue 2, p187-192, 6p
Abstrakt:	An alternative synthesis of 1,3-propanediol 1 having a diethoxyphosphoryldifluoroethyl group was examined. The method readily provided a multi-gram quantity of 1. The propanediol 1 was chemo-enzymatically transformed to acyclic nucleotide analogues for adenosine bisphosphates. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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