Ongoing Transmission of Hepatitis B Virus Infection Among Inmates at a State Correctional Facility.

Autor: Khan, Amy J., Wagner, Karla O., Simard, Edgar P., Bower, William A., Wurtzel, Heather L., Khristova, Marina, Arnold, Kathryn E., Nainan, Omaha V., LaMarre, Madeleine, Bell, Beth P.
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Zdroj: American Journal of Public Health; Oct2005, Vol. 95 Issue 10, p1793-1799, 7p, 1 Diagram, 2 Charts
Abstrakt: Objectives. We sought to determine hepatitis B virus (HBV) infection prevalence, associated exposures, and incidence among male inmates at a state correctional facility. Methods. A cross-sectional serological survey was conducted in June 2000, and susceptible inmates were retested in June 2001. Results. At baseline, 230 inmates (20.5%; 95% confidence interval [CI] = 18.2%, 22.9%) exhibited evidence of HBV infection, including 11 acute and 11 chronic infections. Inmates with HBV infection were more likely than susceptible inmates to have injected drugs (38.8% vs 18.0%; adjusted prevalence odds ratio [OR]=3.0; 95% CI = 1.9, 4.9), to have had more than 25 female sex partners (27.7% vs 17.5%; adjusted prevalence OR=2.0; 95% CI = 1.4, 3.0), and to have been incarcerated for more than 14 years (38.4% vs !7.6%; adjusted prevalence OR = 1.7; 95% CI = 1.1, 2.6). One year later, 18 (3.6%) showed evidence of new HBV infection. Among 19 individuals with infections, molecular analysis identified 2 clusters involving 10 inmates, each with a unique HBV sequence. Conclusions. We documented ongoing HBV transmission at a state correctional facility. Similar transmission may occur at other US correctional facilities and could be prevented by vaccination of inmates. (Am J Public Health. 2005;95: 1793-1799.) [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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