The allylic 7-ketone at the steroidal skeleton is crucial for the antileukemic potency of chlorambucil's active metabolite steroidal esters.

Autor: Evaggelia S Arsenou, Manolis A Fousteris, Anna I Koutsourea, Athanasios Papageorgiou, Venetia Karayianni, Eleftheria Mioglou, Zafiria Iakovidou, Dionysios Mourelatos, Sotiris S Nikolaropoulos
Zdroj: Anti-Cancer Drugs; Nov2004, Vol. 15 Issue 10, p983-990, 8p
Databáze: Complementary Index