Production of a polyketide natural product in nonpolyketide-producing and eukaryotic hosts.

Autor: Kealey, James T., Liu, Lu, Santi, Daniel V., Betlach, Mary C., Barr, Philip J.
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America; 01/20/98, Vol. 95 Issue 2, p505, 5p, 7 Diagrams, 3 Graphs
Abstrakt: Presents a study which investigated polyketide expression in Escherichia coli (E. coli) and Saccharomyces cerevisiae (S. cerevisiae), which are well-established hosts for genetic transformation, protein expression, and high-density growth in liquid medium. Methodology used to conduct the study; Identification of the three basic types of polyketide snythases; Results and discussion of the study.
Databáze: Complementary Index