The Enantiopure 1,2-Diphenylethylenediamine (DPEDA) Motif in the Development of Organocatalysts for Asymmetric Reactions: Advances in the Last 20 Years.

Autor: Oljira, Shilashi Badasa, De Angelis, Martina, Sorato, Andrea, Mazzoccanti, Giulia, Manetto, Simone, D'Acquarica, Ilaria, Ciogli, Alessia
Předmět:
Zdroj: Catalysts (2073-4344); Dec2024, Vol. 14 Issue 12, p915, 31p
Abstrakt: 1,2-Diphenylethylenediamine (DPEDA) is a privileged chiral scaffold being used in the construction of a broad variety of organocatalysts and ligands for enantioselective organic reactions. This molecule gave a significant contribution in the synthesis of structurally different bi/multifunctional organocatalysts. DPEDA played an essential role in the development of organocatalysts capable of yielding important information on the different reaction mechanisms, like enamine, iminium, hydrogen-bonding and anion-binding catalysis. The aim of the present review is to highlight and summarize the achievements reached in the last 20 years (2004–2024) in the chemistry of DPEDA-based organocatalysts for asymmetric synthesis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index