LCRAnnotationsDB: a database of low complexity regions functional and structural annotations.

Autor: Ziemska-Legiecka, Joanna, Jarnot, Patryk, Szymańska, Sylwia, Błaszczyk, Dagmara, Staśczak, Alicja, Langer-Macioł, Hanna, Lucińska, Kinga, Widzisz, Karolina, Janas, Aleksandra, Słowik, Hanna, Śliwińska, Wiktoria, Gruca, Aleksandra, Grynberg, Marcin
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Zdroj: BMC Genomics; 12/27/2024, Vol. 25 Issue 1, p1-14, 14p
Abstrakt: Low Complexity Regions (LCRs) are segments of proteins with a low diversity of amino acid composition. These regions play important roles in proteins. However, annotations describing these functions are dispersed across databases and scientific literature. LCRAnnotationsDB aims to consolidate knowledge about LCRs and store relevant annotations in a single place. To unify redundant annotations, we assigned them categories based on similarity in function, protein structure, and biological process. Categories are organized hierarchically by linking them to Gene Ontology terms. The LCRAnnotationsDB database can be accessed at https://lcrannotdb.lcr-lab.org/. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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