| Abstrakt: |
Researchers at the Institute of Biochemistry have discovered that repeated fasting events sensitize enhancers, transcription factor activity, and gene expression to support augmented ketogenesis in mammals. The study found that mice undergoing alternate-day fasting respond differently to subsequent fasting bouts compared to mice experiencing fasting for the first time. This research sheds light on how past fasting events are "remembered" in hepatocytes, enhancing ketogenesis in response to repeated signals. The study was supported by various funding sources and published in Nucleic Acids Research by Oxford University Press. [Extracted from the article] |
