| Abstrakt: |
A recent study conducted at King Abdullah University of Science and Technology (KAUST) in Thuwal, Saudi Arabia, focused on the detection of nucleobases in DNA sequencing, particularly with the use of Hachimoji DNA, an artificial genetic system with eight nucleotide bases. The research explored the adsorption behavior and electronic transport properties of natural and modified DNA bases on a Janus molybdenum sulfur hydride (MoSH) monolayer using density functional theory (DFT) and non-equilibrium Green's function (NEGF) methods. The findings suggest that the S side of the MoSH monolayer is more effective as a sensing platform for distinguishing between different DNA bases, providing insights for the design of MoSH monolayer-based sensing platforms with potential applications in next-generation DNA sequencing technologies. [Extracted from the article] |
