| Autor: |
Lee, Kevin, Yom, Clairissa, Gilberti, Dante, Tahsin, Saira, Meza, Jacob, Stewart, Jamere, Boone, David, Xing, Yalan |
| Předmět: |
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| Zdroj: |
European Journal of Organic Chemistry; 12/9/2024, Vol. 27 Issue 46, p1-13, 13p |
| Abstrakt: |
Photoredox catalysis and synthetic electrochemistry have begun to find their spot in a synthetic chemist's toolbox. Apart from their use of renewable reagents (light and electricity respectively), these methods have enabled pathways that were previously viewed as inaccessible. It is therefore essential to develop methods to further advance the fields of photoredox catalysis and synthetic electrochemistry. Alkoxyamines have been viewed as prime building blocks for photoredox and synthetic electrochemists because of their facile reactivity to oxidatively cleave C−O bonds. This review begins with addressing the first method developed for generating carbocations via a mesolytic cleavage pathway, and then highlights the recent approaches to utilizing photoredox and synthetic electrochemistry on oxidative cleavage of alkoxyamines for nucleophilic substitution reactions. To demonstrate its applicability, this review also highlights its utilization in the enantioselective synthesis of (−)‐calycanthidine and (−)‐psychotriasine. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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