| Autor: |
Serawat, Kamal K., Meena, Kavita K., Gunsaria, Rajendra K. |
| Předmět: |
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| Zdroj: |
Journal of Advanced Scientific Research; Nov2024, Vol. 15 Issue 11, p16-21, 6p |
| Abstrakt: |
This research work reports the synthesis of novel biologically active cobalt-azomethine coordination complexes [Co(Ln)2Cl2]. The azomethine ligands have been synthesized by the condensation of hydrazine hydrate with aldehydes and ketones, which was then used to synthesize novel Co(II)-azomethine coordination complexes and isolated as solid powdered products. The azomethine ligands and their biologically active Co(II)- azomethine coordination complexes [Co(Ln)2Cl2] were characterized for molecular weight determination, elemental analysis, 1H-NMR and FTIR spectroscopy. The azomethine ligands and their Co(II)-azomethine coordination complexes [Co(Ln)2Cl2] have also been characterized for the antimicrobial activity against several bacterial and fungal species, which has been associated with the standard bactericide ciprofloxacin and fungicide ketoconazole. The outcome of the research has indicated that Co(II)-azomethine coordination complexes [Co(Ln)2Cl2] were found to retain excess antimicrobial activity against bacterial and fungal species as compared to the free azomethine ligands. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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