Rhodium(III)‐Catalyzed (5+2) Annulation Reaction for the Synthesis of Nitro and Cyano Substituted Benzo[b]Oxepines.

Autor: Kalita, Deep J., Bhorali, Pratiksha, Khundrakpam, Supriya, Gogoi, Sanjib
Předmět:
Zdroj: Asian Journal of Organic Chemistry; Dec2024, Vol. 13 Issue 12, p1-5, 5p
Abstrakt: A Rh(III)‐catalyzed annulation reaction of 2‐(2‐nitrovinyl)phenols and disubstituted alkynes is developed to complete the first synthesis of biologically important 4‐nitro substituted benzo[b]oxepines. The same reaction conditions are also applied for the efficient synthesis of 4‐cyano substituted benzo[b]oxepines which have high biological significance. Some of the synthesized 4‐nitrobenzo[b]oxepines are easily transformed to triazole fused dibenzo[b]oxepines. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index