Non-Contact Interaction Between Phorbol Myristate Acetate and Aqueous Alcohol Solutions Under Combined Magnetic Fields.

Autor: Novikov, Vadim V., Yablokova, Elena V., Stepanov, German O., Rodionova, Natalia N., Tarasov, Sergey A., Buravleva, Ekaterina V., Yablonskaya, Olga I., Voeikov, Vladimir L.
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Zdroj: Molecules; Dec2024, Vol. 29 Issue 23, p5814, 18p
Abstrakt: Previous research has demonstrated that a combined magnetic field (CMF) plays a critical role in modifying the properties of aqueous solutions, leading to an increase in the luminol-enhanced chemiluminescence of neutrophils. Using this model, the distant interaction between aqueous solutions was demonstrated, and the role of a CMF in the regulation of this phenomenon was established. In the current study, highly diluted (HD) phorbol myristate acetate (PMA) solution (the donor) was incubated with aqueous ethanol (the acceptor), both in a CMF-generating device and under geomagnetic field (GMF), for 0, 20, and 60 min. After a 60 min incubation at a 0 cm distance with HD PMA under both GMF and CMF, acceptor samples added to neutrophils increased neutrophil chemiluminescence by approximately sevenfold. The ability of HD PMA, which had been incubated with an acceptor, to activate ROS production diminished within 60 min of observation. However, the HD PMA sample remained an effective donor for up to 6 days after preparation. At a 10 cm distance between the donor and acceptor, the activation of the acceptor did not occur. These findings provide new insights into the phenomenon of distant interaction of solutions, whose mechanisms are suggested to be related to the quantum electrodynamics of water molecular dynamic structures. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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