The Association Between Serum Gamma Glutamyl Transferase and Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus; A Cross Sectional Study.

Autor: H. R., Avinash, T. R., Mamatha, Kanth, Mahesh S., S., Madhusudhan, A. G., Arpith
Zdroj: African Journal of Biomedical Research; Sep2024, Vol. 27 Issue 3, p1308-1313, 6p
Abstrakt: INTRODUCTION: Diabetic nephropathy (DN) is one of the major micro vascular complications of diabetes., and it develops in approximately 40% of patients with Type 2 diabetes mellitus. Serum gamma-glutamyltransferase (GGT) is a cell-surface enzyme which is commonly used as a biomarker of liver injury. The relationship between serum β-glutamyltransferase (GGT) and renal dysfunction is inconclusive. In this study, we examined the relationship between serum GGT and diabetic nephropathy (DN) in patients diagnosed with type 2 diabetes mellitus. METHODOLOGY: A total of 119 diabetic patients on an opd basis or admitted as inpatients are included in this study. Complete blood panel was analyzed. GGT., microalbuminuria, urea, creatinine and kidney size were recorded for each participant. CONCLUSION: In our study, elevated GGT was independently associated with diabetic nephropathy in type 2 diabetes patients. Serum GGT is a good indicator for risk of diabetic nephropathy and can be used as a predictor of diabetic nephropathy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index