| Autor: |
Aziz, Rana Rabee, Sadoon, Mohammed M. |
| Zdroj: |
African Journal of Biomedical Research; Sep2024, Vol. 27 Issue 3, p604-611, 8p |
| Abstrakt: |
Background: The biomedical sciences focusing on creating novel medication delivery systems for controlled drug release is fascinating, as nanotubes are specifically employed for drug delivery and the possible improvement of denture liner physical properties. Aims: The research project aims to explore the tensile bond strength and structural morphology of Multiwalled carbon nanotubes (MWCNTs)-Nanonystatin(Nys)-modified hard chairside denture liner following nanosizing nystatin macromolecules for conjugation with MWCNTs and incorporation into chairside hard denture reliners. Methods: The chairside relining material was produced according to the manufacturer's standards, relining specimens were made with a quadrangular shape (43×10×10mm). Tensile bond strength was tested using an Instron Universal Testing Machine, while morphological observations of MWCNTS-Nys-CHDR were conducted by using a Scanning electron microscope and High-Resolution Transmission Electron Microscopy. The chairside hard denture reliner specimens were divided into two groups: the control group (5 specimens) and the modified chairside hard denture reliner (MWCNTs-Nys-CHDR at 0.025%, 0.05%, and 0.1% by weight, 5 specimens each). Results: The bioactive alteration of CHDR led to enhanced tensile bond strength in comparison to the control group. The highest tensile bond strength values were at 0.1% wt. Conclusions: The bioactive alteration of CHDR led to significant improvement in tensile bond strength. All of the specimens utilized in this investigation showed tensile bonding strength values suitable for clinical use, with no structural morphology changes of the bioactive modified denture reliner with Nano-nys conjugated to MWCNTs. It also reveals that MWCNTs preserve their original hollow long tubular form. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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