Racial and Ethnic Disease Phenotype Differences Are Driven by Genetics - Yes.

Autor: Briggs, Farren B.S.
Předmět:
Zdroj: Multiple Sclerosis Journal; 2024 Suppl 5, Vol. 30, p5-8, 4p
Abstrakt: The article explores the genetic factors influencing the prevalence and presentation of multiple sclerosis (MS) across different racial and ethnic groups. It highlights the role of genetic variation, particularly in the HLA-DRB1*15:01 allele, in MS risk and severity. The study suggests that genetic differences, ancestral lineages, and local ancestry may contribute to the observed phenotypic differences in MS across populations. The findings underscore the importance of further research into the genetic components of diverse MS phenotypes, particularly in non-European populations, to advance knowledge and promote research equity. [Extracted from the article]
Databáze: Complementary Index