| Autor: |
Nenaah, Gomah E., Mahfouz, Magdy E., Almadiy, Abdulrhman A., Albogami, Bader Z., Alasmari, Saeed M., Gazzy, Alyaa A., Fadl, Alyaa E. A. |
| Zdroj: |
BioNanoScience; Mar2025, Vol. 15 Issue 1, p1-14, 14p |
| Abstrakt: |
Dengue is a serious arbovirus disease transmitted to humans by female Aedes aegypti mosquitoes. Controlling mosquitoes using synthetic insecticides or indoor sprayings generated serious environmental and health threats, which motivated researchers to develop novel low-risk pest control tools. This work demonstrates a facile low-temperature hydrothermal fabrication of copper oxide nanoparticles (CuONPs) and evaluates their mosquitocidal activity against Ae. aegypti. The optical properties, nanocrystalline nature, and monoclinic structure of CuONPs were characterized using X-ray diffraction (XRD), UV–visible spectroscopy, Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FE-SEM), and transmission electron microscopy (TEM). CuONPs exhibited considerable bioactivity against Ae. aegypti in a concentration- and time-dependent manner. After 24 h, 100% mortality of first, second, and third instar larvae and adults was recorded at 20 µg/mL, whereas 40 µg/mL was enough to cause 100% mortality for all larvae and adults. Larval LC50 after 24 h ranged between 4.1 and 11.1 µg/mL and was 6.8 µg/mL against adults. CuONPs were slightly toxic to Eisenia fetida earthworms (LC50 = 2017.3 µg/L) and were safe toward Gambusia affinis, a larvivorous fish. The results provide evidence for the possibility of using CuONPs as an eco-friendly mosquitocidal tool after establishing their mammalian safety. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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