Treatment of Menstrual Irregularities with Individualized Homeopathic Medicinal Products in Early Reproductive Females: A Double-Blind, Randomized, Placebo-Controlled Trial.
| Autor: | Nag, Usashi, Pal, Rajat Kumar, Saha, Subhranil, Alam, Sk Monsur, Parvin, Tahira, Gole, Raghubir, Debnath, Pintu, Sengupta, Sumana, Koley, Mousumi, Roy, Urmi, Akram, Junayed, Shaikh, Abdur Rahaman, Koley, Munmun, Mukherjee, Shyamal Kumar |
|---|---|
| Předmět: |
CHILDBEARING age
REPEATED measures design PEARSON correlation (Statistics) REPRODUCTIVE health PLACEBOS T-test (Statistics) STATISTICAL sampling BLIND experiment QUESTIONNAIRES HEADACHE FATIGUE (Physiology) INSOMNIA TREATMENT effectiveness RANDOMIZED controlled trials CHI-squared test DESCRIPTIVE statistics SPASTICITY ANALYSIS of variance MENSTRUAL cycle COGNITION disorders MENSTRUATION disorders WOMEN'S health INDIVIDUALIZED medicine COMPARATIVE studies MUSCLE cramps CONFIDENCE intervals HOMEOPATHIC agents BACKACHE REGRESSION analysis |
| Zdroj: | Journal of Integrative & Complementary Medicine; Dec2024, Vol. 30 Issue 12, p1231-1242, 12p |
| Abstrakt: | Objectives: Prevalence of irregular menstrual cycle ranges from 81.7% to 96.3%. Recent research suggested that homeopathy is one of the most popular choices for women with various gynecological disorders. This trial was aimed at differentiating individualized homeopathic medicinal products (IHMPs) from identical-looking placebos in the treatment of menstrual irregularities in early reproductive women. Design: Double-blind, randomized (1:1), two parallel arms, placebo-controlled trial. Setting: D. N. De Homoeopathic Medical College & Hospital, Kolkata, West Bengal, India. Subjects: Ninety-two females with menstrual irregularities. Interventions: Group verum (n = 46; IHMPs plus concomitant care) versus group control (n = 46; placebos plus concomitant care). Outcome Measures: Primary—The proportion of early reproductive females in whom menstrual irregularities can be corrected for consecutive three cycles; Secondary—Menstrual Distress Questionnaire (MDQ) total score; all of them were measured at baseline and every month, up to 4 months. Results: Intention-to-treat sample (n = 92) was analyzed. Group differences were examined by chi-squared tests with categorical outcomes, two-way repeated measure analysis of variance accounting for the time–effect interactions, and unpaired t-tests comparing the mean estimates obtained individually every month. The level of significance was set at p < 0.05 two-tailed. After 4 months of intervention, the group difference in the primary outcome was nonsignificant statistically—IHMPs: 22/46 v/s placebo: 24/46, chi-square (Yates corrected) = 0.043, p = 0.835. The improvement observed in the MDQ total score (F |
| Databáze: | Complementary Index |
| Externí odkaz: |
|