Comparison of Contrast-Enhanced Voiding Urosonography with Standard Fluoroscopic Voiding Cystography for the Diagnosis of Vesicoureteral Reflux: A single-Institute of Children.

Autor: Alshamiri, Kamal, Alsaiady, Moath, Bajaber, Omar, Abounassif, Mazen, Alharbi, Shadi, Almutairi, Abdulelah, Al Moudi, Mansour
Zdroj: Dr. Sulaiman Al Habib Medical Journal; Sep2024, Vol. 6 Issue 3, p124-128, 5p
Abstrakt: Contrast-enhanced voiding urosonography (ce-VUS) is widely used in Europe to diagnose vesicoureteric reflux (VUR) in children. It is highly sensitive and avoids exposure to ionizing radiation. We compared the sensitivity and specificity of ce-VUS to those of VCUG performed on patients in Saudi Arabia and the Middle East to emphasize the agreement between the two modalities in detecting VUR in children with urinary tract infections (UTIs). Aims: To evaluate the diagnostic performance of ce-VUS using a second-generation ultrasound contrast agent for diagnosing VUR and to compare its performance with that of the standard VCUG. Settings and Design: Twenty-eight consecutive children who underwent ce-VUS and VCUG from September to December 2023 were enrolled. Methods and Material: ce-VUS and VCUG were performed simultaneously by two operators using an intravesical infusion of a mixture of ultrasound contrast medium, iodinated contrast medium, and water. Three pediatric radiologists independently reviewed the ce-VUS and VCUG images and reported the presence and degree of VUR (grades I–V). Statistical Analysis Used: This prospective study involved the consecutive recruitment of pediatric patients with suspected VUR. 28 patients (14 boys and 14 girls; 14 years ± 1 month) met the selection criteria. Results: Twenty-three patients yielded similar positive and negative results of VUR on both left and right sides in VCUG and ce-VUS. Only five patients showed discordant results. The diagnostic sensitivities of VCUG and ce-vus for the left VUR were 90% and 91%, respectively, whereas those for the right VUR were both 100%. The specificities of VCUG and ce-vus for the right VUR were 94.44% and 94.74%, respectively, whereas those for the right VUR were both 100%. Conclusions: Considering that radiation exposure among infants and children should be minimized, ce-VUS can potentially replace VCUG as an alternative diagnostic modality for detecting VUR. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje