| Autor: |
Asafova, V. D., Kulakov, S. A., Bortnikova, S. A., Belogorlov, A. A. |
| Zdroj: |
Journal of Engineering Physics & Thermophysics; Nov2024, Vol. 97 Issue 6, p1508-1513, 6p |
| Abstrakt: |
The paper presents the results of investigation into the effects of the composition of a nonwetting liquid (distilled water, physiological solution, and doxorubicin solution) on the kinetics of outflow from hydrophobized Fluka 100 C18 silica gel. A series of measurements was taken regarding the filling of and discharge from the investigated systems in the temperature range of 5 to 40°C with the waiting time between cycles 10–1000 s. Values were obtained for the fraction of the liquid that failed to flow out of a porous material as a function of time and temperature, and also the functions of pore size distribution were recovered for the retained liquid. A reduction was found in the fraction of the retained liquid with increase in temperature and the waiting time. It follows from the obtained results that the determination of the outflow kinetics for a doxorubicin solution with a concentration of up to 1 μM can be carried out without using a medicinal drug. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink