Autor: |
Sun, Yu-Ze, Lin, Guo-Qiang, He, Zhi-Tao |
Předmět: |
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Zdroj: |
Synlett; Jan2025, Vol. 36 Issue 1, p82-86, 5p |
Abstrakt: |
Two novel copper-catalyzed cyclization reactions involving a remote propargylic substitution/cyclization/isomerization cascade are disclosed. Derivatives of the seldomly studied heterocycles thieno[2,3- c ]pyrrole and thieno[2,3- d ]pyridazine are conveniently synthesized in moderate to good yields from primary amines or arylhydrazines through [4+1] and [4+2] reactions, respectively. Preliminary mechanistic experiments corroborated the occurrence of the designed cascade reactions. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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