Asymmetric Total Synthesis of Lobophopyranone A and B.

Autor: Reddy, G. Sudhakar, Choudhury, Utkal Mani, Keerthana, H. Sai, Naik, K. Charan, Mohapatra, Debendra K.
Předmět:
Zdroj: Synthesis; Jan2025, Vol. 57 Issue 1, p99-108, 10p
Abstrakt: The first asymmetric total synthesis and structural confirmation of lobophopyranone A and B have been accomplished from commercially available starting materials. Reagent-controlled Keck–Maruoka allylation, Grignard reaction, chelation-controlled Sakurai allylation, and acid-mediated one-step TBS ether deprotection followed by cyclization are the crucial stages in this synthesis that create the 2,6-disubstituted dihydropyranone component. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index