Abstrakt: |
Researchers at Metro North Hospital and Health Service have explored the use of autologous Epstein-Barr virus-specific adoptive T-cell therapy in a patient with lupus nephritis. This therapy showed promising results, with a reduction in anti-viral and global T-cell activation, improved glomerular filtration rate, and decreased anti-dsDNA antibodies. The study marks the first report of using EBV-specific adoptive immunotherapy to treat lupus nephritis, offering a potential new therapeutic strategy for this condition. For more information, readers can access the full article in Clinical & Translational Immunology. [Extracted from the article] |