Reports on Traumatic Brain Injury from Hebei Medical University Provide New Insights (Astragaloside Iv Ameliorated Neuroinflammation and Improved Neurological Functions In Mice Exposed To Traumatic Brain Injury By Modulating the Perk-eif2a-atf4...).

Předmět:	CENTRAL nervous system diseases BRAIN injuries CELL anatomy CRANIOCEREBRAL injuries INTRACELLULAR space
Zdroj:	Pain & Central Nervous System Week; 12/9/2024, p831-831, 1p
Abstrakt:	Researchers from Hebei Medical University in China conducted a study on traumatic brain injury (TBI) and its pathological mechanisms, focusing on endoplasmic reticulum stress (ER stress) and neuroinflammation. The study found that Astragaloside IV (AS-IV) improved neurological functions in mice with TBI by modulating the PERK-eIF2a-ATF4 signaling pathway. AS-IV was shown to alleviate neuroinflammation and brain damage post-TBI through the PERK pathway, offering new insights for TBI treatment. This research provides valuable information on potential strategies for treating secondary brain injury. [Extracted from the article]
Databáze:	Complementary Index
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