| Abstrakt: |
The article discusses research conducted at the Medical University of South Carolina on the role of the mature microRNA-binding protein QKI in promoting microRNA-mediated gene silencing. The study found that QKI interacts with AGO2 and let-7b to regulate gene silencing at multiple steps, acting as an auxiliary factor in the process. Additionally, QKI was shown to suppress cMYC expression, demonstrating its potential as a tumor suppressor gene. The findings suggest that QKI plays a crucial role in the versatile regulation of miRNA-mediated gene silencing. [Extracted from the article] |
