Research Results from University of Montreal Update Understanding of Biomedicine (Age-Related Choroidal Involution Is Associated with the Senescence of Endothelial Progenitor Cells in the Choroid).

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Zdroj: Genomics & Genetics Weekly; 12/13/2024, p1614-1614, 1p
Abstrakt: A study conducted at the University of Montreal focused on age-related choroidal involution and its association with the senescence of endothelial progenitor cells (EPCs) in the choroid. The research compared EPCs in young and old rats, finding a significant reduction in choroidal thickness and EPCs in older rats. Whole-genome profiling revealed gene modulation related to key signaling processes, suggesting potential strategies to preserve vascular integrity in aging choroids. The study concluded that modifying native EPCs could offer a new approach to prevent degenerative maculopathies. [Extracted from the article]
Databáze: Complementary Index