Abstrakt: |
Researchers at the RIKEN Center for Integrative Medical Sciences in Yokohama, Japan, have published a study on the impact of retrotransposons, a type of transposable element, on cellular responses. Retrotransposons, which make up a significant portion of the human genome, can be reactivated under certain conditions like tumorigenesis and stress, potentially leading to genetic instability. The study explores the dual nature of retrotransposons as genomic parasites and regulatory elements, shedding light on their roles in genetic diversity and innate immunity. The research suggests that dysregulation of retrotransposons could lead to aberrant responses, inflammation, and autoimmune diseases. [Extracted from the article] |