Abstrakt: |
A recent study conducted by National University researchers in the Dominican Republic focused on pharmacogenetic variability in response to prescribed drugs among 197 healthy volunteers. The study examined CYP2D6, CYP2C9, and CYP2C19 alleles and genotypes, revealing an average genomic ancestry of 23.8% European, 42.6% Native American, and 33.6% African. The research highlighted differences in allele frequencies based on genomic ancestry, emphasizing the importance of considering ethnicity in the development of pharmacogenetic guidelines for personalized medicine. The study's findings contribute to the broader goal of ensuring equitable access to personalized medicine for diverse populations. [Extracted from the article] |