New Autism Findings from Princess Nourah Bint Abdulrahman University Published (Perindopril Ameliorates Sodium Valproate-Induced Rat Model of Autism: Involvement of Sirtuin-1, JAK2/STAT3 Axis, PI3K/Akt/GSK-3b Pathway, and PPAR-Gamma Signaling).

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Zdroj: Mental Health Weekly Digest; 12/13/2024, p380-380, 1p
Abstrakt: Researchers from Princess Nourah Bint Abdulrahman University in Riyadh, Saudi Arabia, conducted a study on autism, focusing on the effects of perindopril on a rat model of autism. The study aimed to understand the molecular mechanisms involved in these effects, including sirtuin-1, oxidative stress, inflammatory markers, and various signaling pathways. The results suggested that perindopril could potentially be a promising treatment for autism spectrum disorders. For more information, readers can refer to the original article published in Medicina. [Extracted from the article]
Databáze: Complementary Index