Histopathological Changes in Ovarian Tissues of Rats Underwent Ovarian Ischemia-Reperfusion Injury.

Autor: Atiç, Esranur, Sancar, Muhyiddin, Karabat, Mehmet Uğur, Kaplan, Şehmus, Aşır, Fırat, Akkuş, Murat
Předmět:
Zdroj: Journal of Drug Delivery & Therapeutics; Nov2024, Vol. 14 Issue 11, p58-62, 5p
Abstrakt: This study investigates histopathological changes in ovarian tissues of rats subjected to ischemiareperfusion (I/R) injury, a condition where restored blood flow causes cellular stress and potential damage. Rats were divided into three groups: control, ischemia, and ischemiareperfusion. Histological analysis revealed that ischemic ovaries exhibited increased follicular degeneration, atretic follicles, and inflammatory infiltration. The ischemia-reperfusion group showed even more pronounced damage, including disrupted cellular structures and severe vascular congestion. These findings highlight the exacerbated tissue damage caused by reperfusion, underscoring the complex impact of I/R injury on ovarian tissue integrity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index