Recalcitrant Gram-Positive Bacterial Keratitis Treated with Intrastromal Levofloxacin 1.5% Ophthalmic Solution: A Case Report and Review of Literature.

Autor: Santos, Bobbie Marie M., Poblete, Josept Mari S., Sosuan, George Michael N., Sandoval Jr., Pablito F., Cordero, Billie Jean T., Tirol V., David Ammiel R., Bon Siong, Ruben Lim
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Zdroj: Philippine Journal of Ophthalmology; Jan-Jun2024, Vol. 49 Issue 1, p54-60, 7p
Abstrakt: Objective: This paper demonstrated the effectiveness of intrastromal injection of levofloxacin 1.5% ophthalmic solution in the management of recalcitrant Gram-positive bacterial keratitis. Methods: This is a report on two cases of recalcitrant bacterial keratitis encountered at the External Diseases and Cornea Clinic of the Department of Ophthalmology and Visual Sciences at the Philippine General Hospital. Results: Two middle-aged females presented with bacterial keratitis unresponsive to previous antibiotic treatment with impending corneal perforation. The Gram stain of the corneal scraping in the first case revealed Gram-positive cocci, while the second case showed encapsulated Gram-positive bacilli and encapsulated Grampositive cocci in chains. In both cases, repeated intrastromal injections of levofloxacin 1.5% in addition to increasing the frequency of topical levofloxacin 1.5% resulted in marked improvement in visual acuity and resolution of deep stromal infiltrates and hypopyon. Conclusion: These cases highlighted the utility of intrastromal levofloxacin 1.5% ophthalmic solution in the management of recalcitrant Gram-positive bacterial keratitis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index